side effect

noun

Synonyms of side effectnext
: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
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For example, certain diuretics, antihistamines or stimulants may increase the risk of side effects from heat, according to the CDC. Dinah Voyles Pulver, USA Today, 3 July 2026 Taking more than your body needs can actually cause vitamin toxicity, leading to side effects that range from mild discomfort to serious health problems. Anna Giorgi, Verywell Health, 3 July 2026 That kind of determination may involve job duties, transportation, treatment side effects, fluctuating symptoms and the difference between working sometimes and working consistently. Michelle Mbekeani, Forbes.com, 1 July 2026 One of the lasting side effects of the COVID-19 pandemic and our catastrophically incompetent response to it is the decrease in trust in public health experts and their advice. Ian Miller Outkick, FOXNews.com, 1 July 2026 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 5 Jul. 2026.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

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